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For many people, lifestyle changes like eating a healthy diet, quitting smoking, exercising, limiting stress, avoiding alcohol, and talking to a therapist can cure ED without the use of medication. Among these NO independent targets is the ROCK pathway59, which contributes to tonic smooth muscle cell contraction via calcium sensitization FIG 3a. More research is needed to study its safety and effectiveness. PrEP does not provide protection against STIs, and if not taken consistently is much less effective, so does not replace other prevention options like condoms. Important thing is don t rush things, I have seen many people try to make their penis bigger as soon as possible and jump to very advance exercises only to get serious injury.

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