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Be aware that drugs and alcohol may affect your ability to make good decisions. But keep in mind that this trick is only suitable for small areas. In volunteers with hepatic impairment Child Pugh Class A and B , sildenafil clearance was reduced, resulting in higher plasma exposure of sildenafil 47 for C max and 85 for AUC. Co administration of the HIV protease inhibitor saquinavir, a CYP3A4 inhibitor, at steady state with sildenafil resulted in a 140 increase in sildenafil Cmax and a 210 increase in sildenafil AUC. Your doctor has weighed the risks of you taking this medicine against the benefits they expect it will have for you.

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