2024-12-31T09:06:18+0000

After this time, the organism would then be called a fetus. This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health. Coadministration of apalutamide, a strong CYP3A4 inducer, with drugs that are CYP3A4 substrates can result in lower exposure to these medications. No significant interactions were shown when sildenafil 50 mg was coadministered with tolbutamide or warfarin , both of which are metabolised by CYP2C9.