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Male sexual arousal is a complex process that involves the brain, hormones, emotions, nerves, muscles, and blood vessels, per the Mayo Clinic. CGMP is primarily hydrolyzed and inactivated by the enzyme phosphodiesterase type 5. To find out how marriage affects survival, scientists from the University of Miami investigated 143,063 men with the disease. The study protocol, including Informed Consent protocol, was approved by the University of California, Institutional Review Board.

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