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However, hypogonadism does not activate ROCK2, which is increased in response to testosterone in endothelial cells60. ED treatment involves tackling the cause of the problem, whether this is physical, psychological or a mixture of both. But before we get into the details about how to cure erectile dysfunction naturally and permanently, let s first understand what erectile dysfunction is. If you ve never had a problem getting an erection and keeping it up until you and your partner are both satisfied.

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